vat_wm_ref_region

petpal.preproc.segmentation_tools.vat_wm_ref_region(input_segmentation_path: str, out_segmentation_path: str | None) → ants.ANTsImage

Generates the cortical white matter reference region described in O’Donnell JL et al. (2024).

Reference: O’Donnell JL et al. (2024). PET Quantification of [18F]VAT in Human Brain and Its Test-Retest Reproducibility and Age Dependence. J Nucl Med. 2024 Jun 3;65(6):956-961. doi: 10.2967/jnumed.123.266860. PMID: 38604762; PMCID: PMC11149597.

Requires FreeSurfer segmentation with original label mappings.

Parameters:

• input_segmentation_path (str) – Path to segmentation on which white matter reference region is computed.

• out_segmentation_path (str) – Path to which white matter reference region mask image is saved.

Returns:

wm_erode (ants.ANTsImage) – Eroded white matter reference region mask image.