Reference Tissue Models#

Todo

  • Method to calculate chi-squared from fit,

    \(\chi^2=\Sigma_{i=1}^{n}(x_i-x_{ti})^2/\sigma_i^2\)

Functions#

calc_srtm_tac(→ numpy.ndarray)

Calculate the Time Activity Curve (TAC) using the Simplified Reference Tissue Model (SRTM)

_calc_simplified_frtm_tac(→ numpy.ndarray)

Calculate the Time Activity Curve (TAC) for the Full Reference Tissue Model (FRTM) given the

_calc_frtm_params_from_kinetic_params(→ tuple[float, ...)

Calculates the parameters (coefficients) for the simplified FRTM function

calc_frtm_tac(→ numpy.ndarray)

Calculate the Time Activity Curve (TAC) using the Full Reference Tissue Model (SRTM) with the

fit_srtm_to_tac(→ tuple)

Fit SRTM to the provided target Time Activity Curve (TAC), given the reference TAC, times, and

fit_srtm2_to_tac(→ tuple)

Fit SRTM2 to the provided target Time Activity Curve (TAC), given the reference TAC, times, and

fit_srtm_to_tac_with_bounds(, k2_bounds, bp_bounds)

Fit SRTM to the provided target Time Activity Curve (TAC), given the reference TAC, times, and

fit_srtm2_to_tac_with_bounds(, bp_bounds)

Fit SRTM2 to the provided target Time Activity Curve (TAC), given the reference TAC, times, and

fit_frtm_to_tac(→ tuple)

Fit FRTM to the provided target Time Activity Curve (TAC), given the reference TAC, times, and

fit_frtm2_to_tac(→ tuple)

Fit FRTM2 to the provided target Time Activity Curve (TAC), given the reference TAC, times, and

fit_frtm_to_tac_with_bounds(, k2_bounds, k3_bounds, ...)

Fit FRTM to the provided target Time Activity Curve (TAC), given the reference TAC, times, and

fit_frtm2_to_tac_with_bounds(, k3_bounds, k4_bounds)

Fit FRTM2 to the provided target Time Activity Curve (TAC), given the reference TAC, times, and

fit_mrtm_original_to_tac(tac_times_in_minutes, ...[, ...])

Fit the original (1996) Multilinear Reference Tissue Model (MRTM) to the provided target Time

fit_mrtm_2003_to_tac(tac_times_in_minutes, ...[, weights])

Fit the 2003 Multilinear Reference Tissue Model (MRTM) to the provided target Time Activity

fit_mrtm2_2003_to_tac(tac_times_in_minutes, ...[, weights])

Fit the second version of Multilinear Reference Tissue Model (MRTM2) to the provided target

calc_bp_from_mrtm_original_fit(→ float)

Given the original MRTM (Ichise et al., 1996) fit values, we calculate the binding potential

calc_bp_from_mrtm_2003_fit(→ float)

Given the 2003 MRTM (Ichise et al., 1996) fit values, we calculate the binding potential

calc_bp_from_mrtm2_2003_fit(→ float)

Given the 2003 MRTM2 (Ichise et al., 1996) fit values, we calculate the binding potential

calc_k2prime_from_mrtm_original_fit(fit_vals)

Given the original MRTM (Ichise et al., 1996) fit values, we calculate \(k_{2}^{\prime}\).

calc_k2prime_from_mrtm_2003_fit(fit_vals)

Given the 2003 MRTM (Ichise et al., 2003) fit values, we calculate \(k_{2}^{\prime}\).